22/08/2026 · Blog

MOTS-c : Mitochondrial Research & Quality Guide

Five MOTS-c 40mg peptide vials on a blue laboratory background

MOTS-c is a 16-amino-acid mitochondrial-derived peptide (MDP) that has attracted growing interest in metabolic and mitochondrial research. Unlike many conventional peptides, MOTS-c is associated with the mitochondrial genome, making it particularly interesting for studies of cellular energy regulation.

What Is MOTS-c?

MOTS-c stands for Mitochondrial Open Reading Frame of the 12S rRNA-c.

Key specifications include:

  • CAS Number: 1627580-64-6
  • Molecular Formula: C101H152N28O22S2
  • Molecular Weight: approximately 2174.6 g/mol
  • Sequence: MRWQEMGYIFYPRKLR
  • Length: 16 amino acids

Research involving MOTS-c has explored mitochondrial signaling, cellular metabolism, AMPK-related pathways and metabolic homeostasis.

MOTS-c Reviews: What Matters for Researchers?

Online MOTS-c reviews include both positive claims and negative concerns. However, anecdotal experiences are not a reliable way to evaluate research-grade MOTS-c.

For laboratory procurement, researchers should instead focus on measurable factors such as HPLC purity, molecular identity, COA documentation, batch consistency and storage conditions.

Research-Grade MOTS-c from SUNONE

As a professional MOTS-c manufacturer and peptide supplier, SUNONE provides research-grade MOTS-c for qualified laboratory and manufacturing applications.

Researchers can view purity information, molecular specifications and available documentation on the SUNONE MOTS-c Peptide Product Page.

When choosing a MOTS-c supplier, verified identity and analytical documentation should be considered alongside purity and manufacturing consistency.

Disclaimer

This content is for scientific and educational purposes only. SUNONE MOTS-c is intended for laboratory research and manufacturing use only and is not for human or veterinary use, self-administration, diagnosis or treatment. This article does not constitute medical advice.

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