CJC-1295 with DAC: What Does DAC Actually Change—and Why Should B2B Buyers Care?

CJC-1295 with DAC and CJC-1295 No DAC sound almost identical. Chemically and experimentally, they should not be treated as the same research material.

For laboratories and professional peptide buyers, those three letters — DAC — matter.

What Is CJC-1295 with DAC?

CJC-1295 with DAC (CAS 446262-90-4) is a synthetic long-acting analog of growth hormone-releasing hormone (GHRH).

DAC stands for Drug Affinity Complex.

The modification enables the peptide to interact with endogenous albumin, creating a substantially extended pharmacokinetic profile compared with shorter-acting GHRH-related peptides.

Human research has investigated CJC-1295 in areas including:

GHRH receptor signaling;
GH/IGF-1 axis biology;
peptide pharmacokinetics;
GH secretion patterns;
peptide-protein interactions.

CJC-1295 DAC vs. No DAC: Don’t Mix the Data

This is one of the biggest problems with CJC-1295 content online.

CJC-1295 with DAC and products marketed as CJC-1295 No DAC / Modified GRF 1-29 should not be treated as interchangeable.

The DAC-containing form was specifically designed for prolonged activity.

Published human studies of long-acting CJC-1295 reported sustained changes in GH and IGF-1 and an estimated half-life measured in days rather than minutes.

Interestingly, another human study found that GH secretion remained pulsatile despite the prolonged stimulation.

For researchers, this means the exact molecular form matters when interpreting published literature.

HPLC analysis and laboratory quality control supporting peptide manufacturing and batch verification.

What Do CJC-1295 DAC Reviews Say?

Online experiences are highly mixed.

Some users report perceived changes involving recovery, energy or body composition.

Negative experiences reported online include:

facial flushing;
headache or head pressure;
injection-site reactions;
water retention;
fatigue;
other unwanted systemic reactions.

These experiences cannot establish safety or efficacy.

Online reports often involve other peptides or compounds, while actual identity, purity and contaminants are rarely independently verified.

Anecdotes are not analytical data.

Choosing a CJC-1295 DAC Supplier: Verify More Than Purity

1. Confirm It Is the DAC Form

Documentation should clearly identify the product as:

CJC-1295 with DAC / CJC-1295 DAC / DAC:GRF

rather than simply “CJC-1295.”

2. Review HPLC Purity

CJC-1295 DAC HPLC data can provide information about chromatographic purity and peptide-related impurities.

But:

HPLC purity does not independently prove molecular identity.

3. Check MS Identity Data

Where available, mass spectrometry or LC-MS can provide additional evidence supporting the expected molecular identity.

For modified peptides, evaluating identity and purity together is particularly important.

4. Request a Batch-Specific COA

A useful CJC-1295 Certificate of Analysis should correspond to the actual production lot.

Depending on research requirements, B2B buyers may consider reviewing:

HPLC purity;
MS/LC-MS identity data;
batch or lot number;
molecular specifications;
SDS;
storage conditions;
applicable QC documentation.

Laboratory evaluation supporting peptide inquiries, product specification review and quotation preparation.

CJC-1295 with DAC from Sunone

Sunone (Hong Kong) Biopharmaceutical International Technology Co., Limited supplies CJC-1295 with DAC for qualified laboratory, analytical and biopharmaceutical research applications.

Current product information includes:

Product: CJC-1295 with DAC
Synonyms: CJC-1295 DAC / DAC:GRF / CJC 1295
CAS: 446262-90-4
Molecular Formula: C165H269N47O46
Molecular Weight: 3647.2 g/mol
Grade: Research Grade
Purity: ≥98% by HPLC
Form: Lyophilized Solid
Documentation: COA, HPLC and MS documentation available according to batch specification

Sunone can also discuss custom synthesis, vial filling, labeling, OEM/ODM packaging and bulk requirements for qualified B2B projects.

Looking for a CJC-1295 with DAC research peptide supplier with batch-specific analytical documentation?

View CJC-1295 with DAC Specifications ：

CJC-1295 (with DAC)

Send Sunone your required quantity, purity specification, packaging format and analytical-documentation requirements for a B2B quotation.

CJC-1295 DAC FAQ

What does DAC mean in CJC-1295?

DAC means Drug Affinity Complex, a modification associated with the long-acting characteristics of CJC-1295.

Is CJC-1295 with DAC the same as CJC-1295 No DAC?

No. They should be treated as distinct research materials, and scientific findings involving one form should not automatically be attributed to the other.

What is the CAS number of CJC-1295 with DAC?

Sunone lists CAS 446262-90-4 for CJC-1295 with DAC.

What should buyers request from a CJC-1295 DAC supplier?

Professional buyers may consider reviewing batch-specific COA, HPLC purity, MS/LC-MS identity data, specifications, SDS and lot traceability.

For more information, please click here.

This content is provided for scientific and educational purposes only. SUNONE research peptide is for qualified labrtorynt, diagnois, druc tor mmatct or veteimant, use.research only, Not for human consumption, clinical treame. Purchasers are responsible for complying with applicable laws and regulations in their jurisdiction.