20/09/2026 · Blog

Melanotan I Research Peptide: Why Afamelanotide Name Recognition Is Not Enough

Melanotan I MT-1 peptide 10mg vial for research use

Melanotan I, MT-1, NDP-MSH and afamelanotide often appear in the same search results. For professional B2B buyers, however, a familiar molecule name does not guarantee the same product standard.

When sourcing Melanotan I research peptide, molecular identity, purity and batch documentation matter more than the label alone.


What Is Melanotan I?

Melanotan I (MT-1, CAS 75921-69-6) is a synthetic analogue of alpha-melanocyte-stimulating hormone (α-MSH).

It is also associated with names such as:

  • Melanotan-1;
  • MT-1 peptide;
  • NDP-MSH;
  • Afamelanotide research analog;
  • Alpha-MSH analog.

The peptide was designed with amino-acid substitutions that increase stability compared with native α-MSH.

In qualified laboratory environments, Melanotan I may be used in research involving:

  • melanocortin receptor signaling;
  • MC1R-related pathways;
  • melanogenesis;
  • peptide-receptor interactions;
  • pigmentation biology;
  • analytical peptide characterization.
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Melanotan I vs. Afamelanotide Drug Products

This distinction is important.

Afamelanotide is the active substance in the regulated prescription implant SCENESSE, which is approved for a specific indication involving erythropoietic protoporphyria.

That approval applies to a defined pharmaceutical product, formulation, manufacturing process and regulatory specification.

It does not mean that every research-grade material labeled “Melanotan I” or “afamelanotide” is an approved pharmaceutical product.

For B2B research procurement, the supplied material should be evaluated on its own batch-specific analytical documentation.


What Do Melanotan I Reviews Say?

Online experiences are mixed.

Some users report:

  • increased pigmentation;
  • more gradual color development than Melanotan II;
  • fewer perceived central side effects.

Negative experiences discussed online include:

  • nausea;
  • flushing;
  • fatigue;
  • uneven pigmentation;
  • darkening of freckles or moles.

These observations are anecdotal.

The exact identity, purity, formulation, other substances and individual biological factors are usually unknown.

Online testimonials therefore cannot establish the quality, safety or performance of a research-grade batch.


Choosing a Melanotan I Supplier: What Should B2B Buyers Verify?

1. Confirm the Exact Identity

Documentation should clearly identify the material as:

Melanotan I / MT-1 / NDP-MSH / Afamelanotide Research Analog

and match the expected molecular specification.

2. Review HPLC Purity

Melanotan I HPLC testing can provide information about chromatographic purity and peptide-related impurities.

However:

A high HPLC percentage does not independently confirm molecular identity.

3. Review MS or LC-MS Data

Where available, Melanotan I mass spectrometry or LC-MS can provide additional support for the expected molecular species.

For modified peptides, identity and purity should be considered together.

4. Request a Batch-Specific COA

A professional Melanotan I Certificate of Analysis should correspond to the actual production lot.

Depending on the research application, professional buyers may consider reviewing:

  • HPLC purity;
  • MS or LC-MS identity;
  • molecular weight;
  • batch or lot number;
  • product specifications;
  • SDS;
  • storage requirements;
  • applicable impurity information.
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Melanotan I Research Peptide from Sunone

Sunone (Hong Kong) Biopharmaceutical International Technology Co., Limited supplies Melanotan I for qualified laboratory research, analytical development and manufacturing applications.

Current product information includes:

Product: Melanotan I (MT-1)
Synonyms: Melanotan-1 / MT-1 / Afamelanotide Research Analog / Alpha-MSH Analog
CAS: 75921-69-6
Molecular Formula: C78H111N21O19
Molecular Weight: 1646.9 g/mol
Grade: Research Grade
Purity: ≥99% by HPLC
Form: Lyophilized Powder
Storage: 2–8°C, protected from light
Documentation: COA, SDS and Specification Sheet available

Looking for a Melanotan I research peptide supplier with batch-specific analytical documentation?

View Melanotan I Specifications:

Send Sunone your required quantity, specification, packaging format and analytical-documentation requirements to discuss a B2B quotation.

Melanotan I FAQ

What is another name for Melanotan I?

Melanotan I is commonly associated with MT-1, NDP-MSH and afamelanotide-related research terminology.

What is the CAS number for Melanotan I?

Sunone lists Melanotan I as CAS 75921-69-6.

Is Melanotan I the same as Melanotan II?

No. Melanotan I and Melanotan II are distinct alpha-MSH analogues with different structures and pharmacological profiles.

Does afamelanotide drug approval mean research-grade Melanotan I is an approved medicine?

No. Regulatory approval applies to the specific approved finished pharmaceutical product and its defined formulation and manufacturing controls.

What should buyers request from a Melanotan I supplier?

Professional buyers may consider reviewing a batch-specific COA, HPLC chromatogram, MS/LC-MS identity information, molecular specifications, SDS and lot traceability.


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For research and manufacturing use only. Products are supplied to qualified businesses in compliance with the laws and regulations of the destination country. Not intended for personal, diagnostic, or therapeutic use unless duly registered and authorized.