“Delta Sleep-Inducing Peptide” sounds like a conclusion. Scientifically, it is better treated as a research name.
For professional laboratories sourcing DSIP / Emideltide, this distinction matters.
The peptide itself has a clear molecular identity:
WAGGDASGE
But its proposed role as a universal “sleep-inducing” molecule is much less certain.
That makes DSIP a useful example of why research buyers should separate:
Product name → Molecular identity → Analytical quality → Biological evidence
What Is DSIP?
DSIP (Delta Sleep-Inducing Peptide), also known as Emideltide, is a synthetic nonapeptide composed of nine amino acids:
Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
One-letter sequence:
WAGGDASGE
Common identifiers include:
CAS: 62568-57-4
Molecular Formula: C35H48N10O15
Molecular Weight: approximately 848.8 g/mol
DSIP has been investigated in sleep, neuroendocrine and physiological research for several decades.
Does DSIP Really “Induce Sleep”?
The answer is more complicated than the name suggests.
Early studies reported changes in sleep duration, sleep structure or sleep efficiency in some subjects.
However, controlled human studies also found weak, inconsistent or clinically limited effects.
Later scientific reviews questioned whether DSIP should be regarded as an established endogenous sleep-regulating factor at all.
For research buyers, this is important:
The name “Delta Sleep-Inducing Peptide” should not be treated as a proven therapeutic claim.
What Is Much Clearer? The Molecular Identity
While DSIP physiology remains debated, its synthetic peptide identity is much more straightforward.
A research batch intended to represent DSIP should correspond to the expected nine-residue sequence:
WAGGDASGE
That means a professional buyer can ask objective analytical questions:
- Does the COA specify the expected sequence?
- Does the molecular mass correspond to the intended DSIP form?
- Does HPLC support the stated chromatographic purity?
- Does MS or LC-MS support molecular identity?
- Is the chemical form clearly identified?
These questions are more reproducible than relying on the product name alone.
DSIP Parent Peptide vs DSIP Acetate
Another useful distinction is chemical form.
The parent peptide is commonly represented as:
H-WAGGDASGE-OH
DSIP can also appear in records or specifications as an acetate-containing form.
That means molecular-weight and analytical specifications should be interpreted together with the stated chemical form.
For B2B research sourcing:
DSIP name alone ≠ complete specification
A stronger documentation chain is:
Sequence → Terminal Form → Counterion/Salt Form → Molecular Mass → HPLC → MS/LC-MS → Batch COA
Why HPLC Purity Alone Is Not Complete Identity
A specification such as ≥99% HPLC can provide useful chromatographic information.
But purity and identity are not the same analytical question.
A large principal HPLC peak does not independently prove that the material is the intended WAGGDASGE peptide.
For sequence-defined research peptides, analytical documentation should therefore support both:
What the material is
and
How pure that material is.
What Do DSIP Reviews Say?
Online experiences are highly mixed.
Positive anecdotal reports sometimes mention perceived:
- better sleep quality;
- improved ability to remain asleep;
- more restful sleep;
- improved next-day feeling.
Negative comments include:
- no noticeable effect;
- difficulty falling asleep;
- paradoxical wakefulness;
- hangover-like feeling;
- inconsistent sleep changes.
These reports do not establish DSIP safety, efficacy or research-material quality.
Product identity, source, purity, chemical form, concurrent substances and individual health conditions are usually unknown.
What Should a B2B Buyer Verify?
When comparing a DSIP supplier, professional laboratories may consider reviewing:
Exact Sequence
Confirm Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu / WAGGDASGE.
Chemical Form
Verify terminal form and relevant counterion or acetate information.
HPLC Purity
Review the chromatogram for the actual production lot.
MS / LC-MS Identity
Where applicable, confirm that molecular-mass data support the intended DSIP species.
Impurity Profile
Review relevant peptide-related substances or degradation products.
Batch-Specific COA
Generic specifications should not replace lot-specific analytical documentation.
Lot Traceability
The material, vial label, COA and analytical records should correspond to the same batch.
DSIP Research Peptide from Sunone
Sunone (Hong Kong) Biopharmaceutical International Technology Co., Limited supplies DSIP / Delta Sleep-Inducing Peptide for qualified laboratory research and biotechnology manufacturing applications.
Current listed specifications include:
Product: DSIP
Full Name: Delta Sleep-Inducing Peptide
Synonym: Emideltide
Sequence: WAGGDASGE
CAS: 62568-57-4
Molecular Formula: C35H48N10O15
Molecular Weight: approximately 848.8 g/mol
Grade: Research Grade
Purity Specification: ≥99% HPLC
Form: Lyophilized Powder
Storage: 2–8°C, protected from light
Documentation: COA, SDS and Specification Sheet available
Current listed formats include:
5 mg × 10 vials
10 mg × 10 vials
Exact sequence, purity, chemical form and analytical characteristics should always be confirmed against the current batch-specific documentation.
Looking for a DSIP supplier with B2B analytical documentation?
View Sunone DSIP Specifications ：
Contact Sunone with your required quantity, analytical-documentation requirements, packaging format and OEM/ODM project specifications for a current quotation.
FAQ
What is the DSIP sequence?
The commonly reported DSIP sequence is WAGGDASGE, corresponding to Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu.
Is DSIP also called Emideltide?
Yes. Emideltide is used as a synonym for Delta Sleep-Inducing Peptide.
What is the CAS number of DSIP?
Sunone lists DSIP as CAS 62568-57-4.
Is DSIP proven to treat insomnia?
No. Historical human studies produced mixed and generally limited evidence, so the product name should not be interpreted as proof of clinical efficacy.
Does ≥99% HPLC prove DSIP identity?
No. Chromatographic purity and molecular identity are different analytical questions.
Why should DSIP chemical form be specified?
Parent DSIP and acetate-containing forms can have different formula-weight specifications, so the exact form should match the applicable batch documentation.
This content is provided for scientific and educational purposes only. SUNONE research peptide is for qualified labrtorynt, diagnois, druc tor mmatct or veteimant, use.research only, Not for human consumption, clinical treame. Purchasers are responsible for complying with applicable laws and regulations in their jurisdiction.
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